NON-NEOVASCULAR AMD: CASE REPORT #2

A male participant, aged 55, was recruited with a diagnosis of non-neovascular AMD (age-related macular degeneration). The participant underwent a therapeutic regimen of Light Modulation® Low-Level Light Therapy (LM® LLLT) through the eye-light® solution. At baseline, the participant’s best-corrected visual acuity was ascertained to be 25 letters on the Early Treatment Diabetic Retinopathy Study (ETDRS) chart, and Spectral-Domain Optical Coherence Tomography (SD-OCT) revealed a substantial pigment epithelial detachment (PED) accompanied by subretinal fluid at its apex. 

The therapeutic protocol encompassed one session per week for a duration of four weeks, followed by one session bi-weekly for an additional two months. At a one-month follow-up subsequent to the final treatment, there was a complete reabsorption of the subretinal fluid and a collapse of the pigment epithelial detachment, with no residual retinal atrophy. The best-corrected visual acuity was recorded at 60 ETDRS letters.

FIG. 1
The picture delineates the SD-OCT images at baseline (A) which exhibit a pronounced pigment epithelial detachment (PED) with subretinal fluid. The SD-OCT image at the one-month follow-up (B) reveals a flattening
of the PED with the persistence of flat PED accompanied by hyper/hyporeflective material.

The SD-OCT image at the three-month follow-up (C) demonstrates further flattening of the PED.

FIG. 2
The exhibit portrays the baseline fundus autofluorescence (FAF) which exhibits a hyperautofluorescent ring at the periphery of the PED.
The three-month follow-up image reveals isoautofluorescence in the macular region without any legacy of retinal pigment epithelial atrophy.

FIG. 3
Illustrates the microperimetry at baseline (A) which shows a reduction in retinal sensitivity in the macular area with a mean value of 7.4 dB. The microperimetry at the three-month follow-up (B) exhibits a significant enhancement in retinal sensitivity in the macular area with a mean value of 26.5 dB.